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Multiple Myeloma

Multiple MyelomaPet supplement for Multiple Myeloma in dogs and cats.

Herbal remedies to help adjunctively treat multiple myeloma in dogs and cats.

The immune system is a complex array of cells that are found throughout your pet’s body. Immune cells are designed to function in conjunction with one another to provide a fortified defense against unwanted invaders. It is an intricate system that keeps your pet healthy and protects them against all sorts of invaders including allergens, viruses, bacteria, microbes, parasites and toxins.

The immune system is also directed at facilitating normal function and is not intended to be suppressed or stimulated. In cases of dysfunction, an animal’s body requires whole body systemic support. If your pet’s immune system is weakened, every body system is at risk.

Multiple Myeloma (MM) is a cancer of plasma cells, specific types of B-lymphocytes (white blood cells) which produce antibodies as part of the body’s immune system and is attributed to bone infiltration and destruction of the bone. Multiple Myeloma is a relatively uncommon cancer and there is no gender or breed predilection in dogs or cats. The average age at the time of diagnosis is 8-9 years for dogs and for cats, between 6-13 years.

Three defining features must be present for a diagnosis of multiple myeloma:

Immune protein from a single clone of cells (known as a monoclonal gammopathy);

A spike in the gamma region of a protein analysis of the blood (known as a protein electrophoresis);

Cancerous plasma cells or a high number of plasma cells in the bone marrow (known as plasmacytosis);

Destruction of areas of bone (known as lytic bone lesions);

A particular type of protein found in the urine (known as Bence Jones [light-chain] proteinuria).

Symptoms depend on the location and extent of the disease and include:

Weakness

Sluggishness

Lethargy

Lameness (approx. 50% of cases)

Bone pain and weakness (approx. 60 percent of cases)

Concurrent destruction of areas of bone

Hemorrhage (i.e. petechiae on mucous membranes, gingival bleeding or bleeding from the nose)

Fever

Partial paralysis

Dementia with generalized discomfort or uneasiness (approx. 11 percent of cases)

Labored breathing

Increased thirst and increased urination (approx. 25 percent of cases)

Increased levels of calcium in the blood or kidney dysfunction

Urinary incontinence

Enlarged liver and spleen

Excessive bleeding from needle punctures to collect blood or to administer intravenous medications and/or fluids

Bleeding involving the gastrointestinal tract

Bleeding, especially from the nose or moist tissues of the mouth, eyes, and other areas of the body in approx. 36 percent of cases

Bleeding in the back part of the eye and blindness, retinal hemorrhage, or dilated retinal vessels approx. 35 percent of cases

Pale gums and other mucous membranes

Detached retina

Glaucoma

Inflammation of the front part of the eye including the iris

Coma (rare)

Pets may also experience recurrent infections, non-regenerative anemia, hypercalcemia, pathologic bone fractures, and/or seizures.

Secondary complications include kidney failure, immuno suppression, clotting disorders, chronic anemia, cardiac insufficiency, and neurologic dysfunctions.

The exact cause of MM is unknown in dogs or cats. In people damage to DNA or chromosomes are possible causes.

The clinical signs of multiple myeloma vary, affect many organs and body systems and may be present for up to 1 year before diagnosis is made.

Herbal Remedies:

Herbal remedies have a long history of use for the adjunctive treatment of Multiple Myeloma as well as all types of cancer and tumors, to slow and limit progression of tumors and aberrant cells that cause tumors, as an adjunctive support for Multiple Myeloma, to promote healthy cell response, to boost immunity and to limit inflammation, to balance the immune system and for its anti-cancerous and anti-tumorous plant actions. 

Get Well Soon  (learn more) is as an immune booster, an adjunctive cytotoxic (kills cancer cells) therapy against cancer cells and complementary therapy in cancer protocols due to its active content of Annonaceous acetogenins, for its significant anti-tumorous (slows growth), anti-cancerous activity (inhibits anaerobic cells while protecting healthy cells), broad-spectrum internal and external antimicrobial, anti-bacterial, anti-fungal and anti-viral properties against infection, for cysts and tumors, including fibrous, fatty, sebaceous tumors including cutaneous mast cell tumors (mastocytomas, mast cell tumors, sarcomas), lipomas, histiocytomas, adenomas hyperplasia and papillomas. Also used for the following types of tumors: hind quarter, deep tissue, lesions, polyps, warts, basal and mast cell, bone, brain, heart, liver, kidney, bladder, mammary, skin, stomach, eye, ear, nose, mouth and leg tumors.

I Feel Good –  (learn more) promotes healthy immune response, reduces all types of inflammation, provides dermal support and growth of healthy cells and tissues in the body’s defense mechanism, reduces the histamine trigger for contact allergies, seasonal and chronic allergens, pathogens, skin rashes, infections, hot spots, inflammation, swelling, hair loss, itching and geriatria (dull coat, lethargy), for all types of arthritis, including Degenerative Joint Disease, Osteoarthritis, Osteoporosis, Rheumatoid Arthritis (RA) and symptoms associated with rheumatism, including pain, strains, injuries, muscle pain, swelling and lack of mobility; plus contains prebiotics and probiotics useful in balancing digestive health and function plus much more. 

Joint Ease Super Dog & Cat – (learn more) contains plant and marine extracts that promote preventative and reparative support to rebuild tissue, joints, bones and muscles; supports healthy immune and inflammatory response; for rheumatism; for arthritis, osteoarthritis, osteoporosis, rheumatism, Degenerative Joint Disease (DJD), Intervertebral Disk Disease (IDD) & arthrosis; for muscle pains, strains, injuries and other degenerative joint related diseases; for pain; as a pain reliever for swelling and lack of mobility; for overall optimal health and function & as a natural alternative for tumors and cysts.

Dog & Cat Kryptonite (learn more) supports hypothalamic-pituitary adrenal (HPA) function, enables the body to respond normally to stress and metabolic demands while supporting the glands' ability to rebuild and regenerate, supports healthy energy levels and vitality, promotes cognitive function and memory performance, for lethargic, aging or convalescing animals, regulates the organs which secrete hormones, including the pituitary, parotid, thyroid and adrenal glands, the pancreas, and the testes; stimulates the hypothalamus, supports endocrine function, the central nervous, digestive, immune and reproductive systems.

Life’s An Itch - (learn more) is used to promote optimal immune response, reduces all types of allergic (acute and chronic) reactions by stopping histamine response, reduces respiratory disorders, relieves wheezing, chest discomfort and sinus inflammation, soothes smooth muscles and tissues and alleviates respiratory congestion, including asthma, bronchitis, pneumonia, laryngitis, esophaghitis (GERD, reflux), rhinitis, sinusitis, bronchitis, COPD; relieves viral and bacterial infections, hot spots, remedies skin allergies and irritations, soothes itchy skin and coat in dogs and cats, and works to cut recovery time and prevent recurring infection. 

Conventional Remedies:

Your vet will conduct a history of physical examination as well as a detailed analysis of primary and secondary symptoms. Your vet will also conduct an ophthalmological examination. If your pet's eyes are showing symptoms of a diseased state and a complete blood profile, including a chemical blood profile, a complete blood count and a urinalysis to rule out infections, other types of tumors, and immune-mediated illnesses. Diagnostic imaging will include X-rays of the vertebra and limbs to look for bone lesions, and ultrasound to examine the internal organs.

Your veterinarian may need to refer you to a veterinary oncologist for the latest information regarding treatment of this disease. Your dog or cat may be hospitalized if there are high levels of urea - waste products and calcium in the blood. Also, if there is a bleeding disorder, or a significant bacterial infection, hospitalization may be required. A blood-cleansing procedure may be used, or blood may be withdrawn and replaced with an equal volume of fluids.

If possible, radiation therapy may be used on isolated areas, with the goal of curing the disease, or only to control signs and improve your dog’s condition. If there is a concurrent bacterial infection, it will be treated aggressively with antibiotics.

If your dog or cat is being treated with radiation or chemical therapy, it will also need to be guarded against opportunistic infections that can result from the expected lowered immune response (known as immune compromised – a result of the treatment that is used to stop the growth of cancerous cells in the body). You will need to take care to prevent bacterial infections from occurring, such as those caused by puncture wounds from dog or cat fights. Dietary changes will be necessary if your dog is in kidney failure. Affected areas that are non responsive to chemotherapy, or single, solitary lesions may be removed surgically.

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